Hypoderma spp. ınvestıgatıon of dynamıc Thıol dısulfıde balance ın ınfested cattle
Abstract
Hipodermiasis in cattle is a parasitic disease caused by Hypoderma bovis and Hypoderma lineatum type fly larvae. The disease, which mostly affects young cattle, causes economic losses such as developmental delay, decrease in meat and milk yield, and inability to use the back skin as a result of being punctured by the larvae. This study aimed to determine serum total thiol, native thiol, disulfide, interleukin-1, IL-6, and tumor necrosis factor-α levels in Hypoderma-infested cattle. In the study, 15 Hypoderma infested cattle diagnosed by clinical examination and 10 healthy cattle for control purposes were used. Serum total thiol, native thiol and disulphide levels of the sick animals were determined as 406.84 ± 8.33 μmol/L, 297.62 ± 5.24 μmol/L, 54.61 ± 4.83 μmol/L, respectively. interleukin-1, interleukin-6 and tumor necrosis factor-α were detected as 41.98 ± 4.37 pg/mL, 94.11 ± 8.49 pg/mL, 82.29 ± 9.12 pg/mL in infested animals. Total thiol, native thiol and disulfide values of infested animals were determined to be lower than the healthy control group, and interleukin-1, interleukin-6, and tumor necrosis factor-α were higher than those of healthy animals. As a result, interleukin-1, interleukin-6, and tumor necrosis factor-α values were determined to be high, and total thiol and native thiol levels were low in cattle with hipodermiasis.
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