Importance of Specific and Unspecific Tests to Diagnosis Syphilis in Blood Donors

  • Milagros Montiel Department of Microbiology, Professional Immunology Practice, School of Bioanalysis, Faculty of Medicine, Universidad del Zulia, Maracaibo, Venezuela.
  • Julia Arias Department of Microbiology, Professional Immunology Practice, School of Bioanalysis, Faculty of Medicine, Universidad del Zulia, Maracaibo, Venezuela.
  • Elieth Pozo Department of Microbiology, Professional Immunology Practice, School of Bioanalysis, Faculty of Medicine, Universidad del Zulia, Maracaibo, Venezuela.
  • Adriana Mogollón Department of Microbiology, Professional Immunology Practice, School of Bioanalysis, Faculty of Medicine, Universidad del Zulia, Maracaibo, Venezuela.
Keywords: Syphilis, donors, enzymatic immune-analysis, immune-chromatography, venereal, disease research laboratory, unheated serum reagin

Abstract

In order to improve the laboratory diagnosis of syphilis as an infectious and contagious disease in blood donors, we performed this study to determine the reliability of the specific: Enzyme Immunoassay (Elisa) and Immune-chromatography (IC) tests, the unspecific: Venereal Disease Research Laboratory (VDRL) test and the Unheated serum regain (USR) Serologic tests to rule out syphilis from blood donors of the Dr Adolfo Pons Hospital in Maracaibo, Zulia state. We analyzed 481 sera from apparently healthy blood donors, male and female, 18 to 60 years of ages. From the samples analyzed by Elisa 10 were positive (2.07%) and 8 (1.66%) by IC. VDRL detected 4 (0.82%) reactive sera and USR just 2 (0.421%). We concluded that Elisa with VDRL are the safest and more reliable tests to rule out syphilis from blood donors, since they gave in parallel reliable results to assure the quality of blood to be transfused

Published
2008-09-08
How to Cite
1.
Montiel M, Arias J, Pozo E, Mogollón A. Importance of Specific and Unspecific Tests to Diagnosis Syphilis in Blood Donors. Kasmera [Internet]. 2008Sep.8 [cited 2024May19];36(2):169-76. Available from: https://www.produccioncientificaluz.org/index.php/kasmera/article/view/4834
Issue
Vol. 36 No. 2 (2008)
Section
Original Articles

Copyright (c) 2008 Milagros Montiel, Julia Arias, Elieth Pozo, Adriana Mogollón

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